Periopathogen Kills in Biofilm

Professor Michael Wilson and his colleagues at University College London have studied the effects of photodisinfection on biofilm for more than 20 years. The early UCL studies concluded that gram negative bacteria are preferentially targeted by the photodisinfection process due to characteristics of their outer morphology. This bias towards gram negative bacteria is beneficial in the treatment of periodontal disease, which is primarily associated with these pathogens. UCL's pioneering research later established photodisinfection as lethal to biofilm. The chart pictured demonstrates the efficacy of photodisinfection against a trio of these pathogens, P. gingivalis, F. nucleatum and A. actinomycetemcomitans, all as single-species biofilms.

This data was published separately in the proceedings of the SPIE.